Regioselective Nitration of (2E)-3-Aryl-2-(4-arylthiazol-2-yl)acrylonitriles

The reaction of (2E)-3-aryl-2-(4-aryl-1,3-thiazol-2-yl)acrylonitriles with an excess of nitric acid in AcOH proceeds regioselectively to afford previously unknown (2E)-3-aryl-2-(4-aryl-5-nitro-1,3-thiazol-2-yl)acrylonitriles in 82–96% yields.

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Publication Details

Journal
Russian Journal of General Chemistry
Published
2024-10-01
DOI
https://doi.org/10.1134/s1070363224100025
Citations
5
Primary Topic
Synthesis of heterocyclic compounds
Type
article
Field-Weighted Citation Impact
1.25
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article

Regioselective Nitration of (2E)-3-Aryl-2-(4-arylthiazol-2-yl)acrylonitriles

Inna V. Aksenova, N. A. Pakholka, С. Г. Кривоколыско, Nicolai A. Aksenov et al.
5 citations
Russian Journal of General Chemistry
Synthesis of heterocyclic compounds
1.25
article

Regioselective Nitration of (2E)-3-Aryl-2-(4-arylthiazol-2-yl)acrylonitriles

Inna V. Aksenova, N. A. Pakholka, С. Г. Кривоколыско, Nicolai A. Aksenov, Victor V. Dotsenko
article en
5 citations

Abstract

The reaction of (2E)-3-aryl-2-(4-aryl-1,3-thiazol-2-yl)acrylonitriles with an excess of nitric acid in AcOH proceeds regioselectively to afford previously unknown (2E)-3-aryl-2-(4-aryl-5-nitro-1,3-thiazol-2-yl)acrylonitriles in 82–96% yields.

Russian Journal of General ChemistryVol. 94(10)
Kuban State University (RU), North-Caucasus Federal University (RU), Luhansk State Medical University (UA)
Openalex Percentile: Top 22%
Synthesis of heterocyclic compounds
1.25
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