One-Pot Synthesis of Substituted Benzimidazole-Pyrimidine Derivatives
The main objective of this work is the synthesis of polycyclic molecules of benzo[4,5]imidazo[1,2-a]pyrimidine hybrids by condensation of 2-aminobenzimidazole with the precursor 4-hydroxy-6-methylpyran-2-one utilizing various alcoholic solvents. Structural characterization of the synthesized compounds was conducted using diverse spectroscopic methods (NMR, MS, IR, and CHN). The formation of the obtained structures is explained by a detailed reaction mechanism.
Authors
- Pascal Hoffmann (ORCID: https://orcid.org/0000-0002-8707-3928)
- Fairouz Abboub
- Mokhtar Fodili (ORCID: https://orcid.org/0009-0008-9345-9318)
- Mohammed Amari (ORCID: https://orcid.org/0009-0006-2434-8118)
Institutions
- Université Toulouse III - Paul Sabatier (FR)
- University of Sciences and Technology Houari Boumediene (DZ)
- Ziane Achour University of Djelfa (DZ)
- Molécules d'Intérêt Biologique (FR)
- AMIS - Laboratoire d'anthropologie moléculaire et imagerie de synthèse (FR)
Publication Details
- Journal
- Russian Journal of General Chemistry
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1134/s1070363224100128
- Primary Topic
- Synthesis and biological activity
- Type
- article
- Field-Weighted Citation Impact
- 0.00