Motif-guided identification of KRAS-interacting proteins
These results demonstrate the effectiveness of our workflow in predicting potential interacting proteins for KRAS and deepen the understanding of KRAS-driven tumor mechanisms and the development of therapeutic strategies.
Authors
- Sanan Wu
- Xiangjun Meng (ORCID: https://orcid.org/0000-0003-3075-2425)
- Fang Bai (ORCID: https://orcid.org/0000-0003-0639-8104)
- Xianglei Zhang (ORCID: https://orcid.org/0000-0001-5175-8311)
- Lu Liu (ORCID: https://orcid.org/0000-0003-2683-7215)
- Xiaoyang Gao
- Han Yao (ORCID: https://orcid.org/0000-0002-6175-8072)
- Di Wu (ORCID: https://orcid.org/0009-0001-7369-0220)
Institutions
- Shanghai Jiao Tong University (CN)
- ShanghaiTech University (CN)
- Shanghai Ninth People's Hospital (CN)
- Shanghai Clinical Research Center (CN)
Publication Details
- Journal
- BMC Biology
- Published
- 2024-11-19
- DOI
- https://doi.org/10.1186/s12915-024-02067-w
- Citations
- 1
- Primary Topic
- Protein Kinase Regulation and GTPase Signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.23
Funders
- National Natural Science Foundation of China
- ShanghaiTech University