New genomic resources inform transcriptomic responses to heavy metal toxins in the common Eastern bumble bee Bombus impatiens
Our data represent a large improvement in genomic resources for this important model species-with 10% more genome coverage than previously available, and a high-quality assembly into 18 chromosomes, the expected karyotype for this species. The new gene annotation added 777 new genes. Altered gene expression in response to heavy metal exposure suggests a possible mechanism for how these urban toxins are negatively impacting bee health, specifically by altering protein folding in the brain. Overall, these data are useful as a general high quality genomic resource for this species, and provide insight into mechanisms underlying tissue-specific toxicological responses of bumble bees to heavy metals.
Authors
- Mary M. Gardiner (ORCID: https://orcid.org/0000-0003-1796-6146)
- Rick E. Masonbrink
- Katherine S. Geist (ORCID: https://orcid.org/0000-0002-5311-8913)
- Ryan Fortune
- Emeline Favreau (ORCID: https://orcid.org/0000-0002-0713-500X)
- Frances S. Sivakoff (ORCID: https://orcid.org/0000-0003-3981-7862)
- Christopher D. R. Wyatt (ORCID: https://orcid.org/0000-0001-8033-2213)
- Seirian Sumner (ORCID: https://orcid.org/0000-0003-0213-2018)
- Amy L. Toth (ORCID: https://orcid.org/0000-0003-0824-0933)
- Sarah B. Scott (ORCID: https://orcid.org/0000-0003-3508-7647)
- Sandra M. Rehan (ORCID: https://orcid.org/0000-0001-7210-0316)
Institutions
- Iowa State University (US)
- York University (CA)
- University of Cambridge (GB)
- The Ohio State University at Marion (US)
- University College London (GB)
- The Ohio State University (US)
Publication Details
- Journal
- BMC Genomics
- Published
- 2024-11-19
- DOI
- https://doi.org/10.1186/s12864-024-11040-4
- Citations
- 7
- Primary Topic
- Plant and animal studies
- Type
- article
- Field-Weighted Citation Impact
- 7.20
Funders
- National Science Foundation
- U.S. Department of Agriculture
- Sight Research UK
- National Institute of Food and Agriculture
- Natural Environment Research Council