Identification of fibrosis-associated biomarkers in heart failure and human cancers
FMOD, POSTN, LTBP2, COL1A1, COL8A1, ASPN, and HBB are potential biomarkers for HF and cancer with fibrotic microenvironments. Targeting fibrosis may offer novel therapeutic approaches. Further validation and mechanistic studies are needed. This study contributes to understanding HF and cancer at the molecular level and suggests personalized treatment strategies.
Authors
- Junyu Huo (ORCID: https://orcid.org/0000-0002-1345-1893)
- Si Yan (ORCID: https://orcid.org/0009-0005-1380-0255)
- Can Hou (ORCID: https://orcid.org/0000-0003-0337-0149)
- Fei Sun (ORCID: https://orcid.org/0000-0003-4922-9706)
- Xiaoyu Yang (ORCID: https://orcid.org/0000-0003-4631-6900)
Institutions
- Soochow University (CN)
- The First People's Hospital of Changzhou (CN)
- Changzhou No.2 People's Hospital (CN)
- Changzhou Third People's Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2024-11-19
- DOI
- https://doi.org/10.1186/s12967-024-05759-7
- Citations
- 5
- Primary Topic
- Cardiac Fibrosis and Remodeling
- Type
- article
- Field-Weighted Citation Impact
- 2.01