Real-world improvement in ultra-low-dose thoracic computed tomography scores, systemic inflammatory markers and patient-reported outcome measures after elexacaftor/tezacaftor/ivacaftor treatment
ETI responders, demonstrate significant improvements in CT imaging, circulating cytokines and PROMs, which may be of further use evaluating cystic fibrosis transmembrane conductance regulator modulation treatment response.
Authors
- James Dorgan
- K. Deasy (ORCID: https://orcid.org/0000-0002-1685-249X)
- Barry J. Plant (ORCID: https://orcid.org/0000-0002-4611-6768)
- Tamara Vagg (ORCID: https://orcid.org/0000-0002-6582-2975)
- Owen J. O’Connor (ORCID: https://orcid.org/0000-0002-0276-1335)
- Sarah Twohig
- Desmond M. Murphy (ORCID: https://orcid.org/0000-0002-3419-0274)
- Yvonne McCarthy
- Michael Waldron (ORCID: https://orcid.org/0000-0002-4073-9841)
- Paud O’Regan (ORCID: https://orcid.org/0009-0003-6072-1600)
- Hisham R. Ibrahim (ORCID: https://orcid.org/0000-0002-7809-900X)
- Alexander T. O'Mahony
- Joseph A. Eustace
- Ciara Howlett
- Edel O'Riordan
- Michael M. Maher
- C. Fleming (ORCID: https://orcid.org/0009-0005-3905-5847)
- Janice Mansfield
- L. Kirwan (ORCID: https://orcid.org/0000-0002-4922-6110)
- M. J. H. McCarthy
Institutions
- University College Cork (IE)
- Cork University Hospital (IE)
- Cystic Fibrosis Ireland (IE)
Publication Details
- Journal
- ERJ Open Research
- Published
- 2024-11-19
- DOI
- https://doi.org/10.1183/23120541.00897-2024
- Citations
- 3
- Primary Topic
- Lung Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.26