Strong Correlation Between Double-Strand DNA Breaks and Total Sperm DNA Fragmentation in the Human Ejaculate

While the presence of DSBs in sperm is correlated with the W-SDF present in raw semen samples, the biological mechanisms responsible for DSBs are expressed in different proportions and/or at different levels in ejaculates with higher levels of DNA damage.

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Publication Details

Journal
Archives of Medical Research
Published
2024-11-20
DOI
https://doi.org/10.1016/j.arcmed.2024.103122
Citations
2
Primary Topic
Sperm and Testicular Function
Type
article
Field-Weighted Citation Impact
1.07
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article

Strong Correlation Between Double-Strand DNA Breaks and Total Sperm DNA Fragmentation in the Human Ejaculate

Stephen D. Johnston, Mercedes González-Martínez, Jaime Gosálvez, Alfredo Góngora et al.
2 citations
Archives of Medical Research
Sperm and Testicular Function
1.07
article

Strong Correlation Between Double-Strand DNA Breaks and Total Sperm DNA Fragmentation in the Human Ejaculate

Stephen D. Johnston, Mercedes González-Martínez, Jaime Gosálvez, Alfredo Góngora, Javier Bartolomé, Antonio Prado, Pablo Contreras, José Luís Fernández, Carlos García de la Vega, Carmen López‐Fernández
article en
2 citations

Abstract

While the presence of DSBs in sperm is correlated with the W-SDF present in raw semen samples, the biological mechanisms responsible for DSBs are expressed in different proportions and/or at different levels in ejaculates with higher levels of DNA damage.

Archives of Medical ResearchVol. 55(8)
The University of Queensland (AU), MSD (Mexico) (MX), Hero España (Spain) (ES), Instituto de Investigación Biomédica de A Coruña (ES), Universidad Autónoma de Madrid (ES)
Zero hunger
Openalex Percentile: Top 19%
Sperm and Testicular Function
1.07
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