Integrative analysis of gut microbiome and host transcriptome reveal novel molecular signatures in Hashimoto's thyroiditis
Our study reveals novel molecular signatures linking gut microbiome and host transcriptome in HT, providing new insights into the disease pathogenesis. These findings not only enhance our understanding of the gut-thyroid axis but also suggest potential new directions for therapeutic interventions in HT.
Authors
- Fengxu Xiao
- Zhenting Liu
- Jiangwei Yan (ORCID: https://orcid.org/0000-0002-0359-4508)
- Yipeng Cui
- Fanglin Guan (ORCID: https://orcid.org/0000-0001-5135-3277)
- Miao Li (ORCID: https://orcid.org/0000-0002-5501-2856)
- Ke Chen (ORCID: https://orcid.org/0000-0002-8427-4345)
- Qi Zhou (ORCID: https://orcid.org/0000-0002-4036-4066)
- Yuqi Chen (ORCID: https://orcid.org/0000-0001-9769-1167)
- Lei Zhang (ORCID: https://orcid.org/0000-0002-0045-6863)
- Yu Sun (ORCID: https://orcid.org/0000-0003-4191-1786)
- Jue Jiang (ORCID: https://orcid.org/0000-0001-7984-8802)
- Wen Zhang (ORCID: https://orcid.org/0009-0002-9853-3982)
Institutions
- Shanxi Medical University (CN)
- Second Affiliated Hospital of Xi'an Jiaotong University (CN)
- Qilu Hospital of Shandong University (CN)
- Southern Medical University (CN)
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2024-11-20
- DOI
- https://doi.org/10.1186/s12967-024-05876-3
- Citations
- 8
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- National Natural Science Foundation of China