Effectiveness and safety of low-energy shock wave therapy for digital ulcers associated with systemic sclerosis: A Phase 3 pivotal clinical trial
The study findings indicate the efficacy of extracorporeal shock wave therapy for refractory digital ulcers associated with SSc, which has limited therapeutic options. This therapy is non-invasive and safe and can be used without restriction in combination with other therapies, thus serving as a novel therapeutic method.
Authors
- Yoko Fujita (ORCID: https://orcid.org/0000-0002-2411-5473)
- Hiroaki Shimokawa (ORCID: https://orcid.org/0000-0001-7534-4826)
- Izaya Nakaya (ORCID: https://orcid.org/0000-0002-0792-6514)
- Yuko Shirota (ORCID: https://orcid.org/0000-0002-5551-7889)
- Tomomasa Izumiyama
- Osamu Ishikawa (ORCID: https://orcid.org/0000-0002-7655-0610)
- Hiromitsu Takemori
- Naruhiko Takasawa
- Hidekata Yasuoka (ORCID: https://orcid.org/0000-0002-2405-6282)
- Tomonori Ishii (ORCID: https://orcid.org/0000-0001-5361-5824)
- Hiroshi Fujii (ORCID: https://orcid.org/0000-0002-6885-6492)
- Shih‐Wei Chiu
- Takao Kodera (ORCID: https://orcid.org/0000-0003-3716-1898)
- Takuhiro Yamaguchi (ORCID: https://orcid.org/0000-0002-7961-9417)
- Tsuyoshi Shirai (ORCID: https://orcid.org/0000-0002-6295-3494)
- Shinichiro Saito (ORCID: https://orcid.org/0000-0002-2721-248X)
- Osamu Takai
- Yuichi Takahashi (ORCID: https://orcid.org/0000-0001-9965-5311)
- Hideo Harigae (ORCID: https://orcid.org/0000-0003-4849-7442)
- Yukiko Kamogawa
- Yukio Sato (ORCID: https://orcid.org/0000-0002-4947-6240)
- Yasushi Kawaguchi (ORCID: https://orcid.org/0000-0003-2025-1344)
- Hitoshi Kobayashi
Institutions
- Obayashi (Japan) (JP)
- Fujita Health University (JP)
- Gunma University (JP)
- Tohoku University (JP)
- Iwate Prefectural Central Hospital (JP)
- Aomori Rosai Hospital (JP)
- Tohoku University Hospital (JP)
- Hirosakiaiseikai Hospital (JP)
- Tokyo Women's Medical University (JP)
- Sendai City Hospital (JP)
- Sendai Shakai Hoken Hospital (JP)
- Miyagi Prefecture Sendai Higashi High School (JP)
- Tohoku Medical and Pharmaceutical University Wakabayashi Hospital (JP)
- Tohoku Medical and Pharmaceutical University (JP)
Publication Details
- Journal
- Modern Rheumatology
- Published
- 2024-11-18
- DOI
- https://doi.org/10.1093/mr/roae104
- Citations
- 2
- Primary Topic
- Systemic Sclerosis and Related Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.85