Next-generation mpox vaccines: efficacy of mRNA-1769 compared to modified vaccinia virus Ankara in non-human primates

After the online publication of the research highlight, 1 a reader pointed out that the MVA vaccine used in the original study by Mucker et al. 2 was mistakenly labeled as "Jynneos".The authors have now pointed out in the text, that the comparator vaccine used in the original study was the MVA-572 strain and not the MVA-BN (Jynneos) vaccine.The explanations "vaccine study" and "mpox virus challenge" were added to the first panel of Fig. 1 to clarify the study design.In the lower panel, the antibody functions were provided in more detail to avoid misunderstanding by the readers.The corrected figure is provided below.The main messages of this research highlight are not affected by these corrections.

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Publication Details

Journal
Signal Transduction and Targeted Therapy
Published
2024-11-20
DOI
https://doi.org/10.1038/s41392-024-02058-x
Citations
5
Primary Topic
Poxvirus research and outbreaks
Type
article
Field-Weighted Citation Impact
1.47

Funders

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article

Next-generation mpox vaccines: efficacy of mRNA-1769 compared to modified vaccinia virus Ankara in non-human primates

Leonie Marie Weskamm, Leonie Mayer, Marylyn M. Addo
5 citations
Signal Transduction and Targeted Therapy
Poxvirus research and outbreaks
1.47
article

Next-generation mpox vaccines: efficacy of mRNA-1769 compared to modified vaccinia virus Ankara in non-human primates

Leonie Marie Weskamm, Leonie Mayer, Marylyn M. Addo
article en
5 citations

Abstract

After the online publication of the research highlight, 1 a reader pointed out that the MVA vaccine used in the original study by Mucker et al. 2 was mistakenly labeled as "Jynneos".The authors have now pointed out in the text, that the comparator vaccine used in the original study was the MVA-572 strain and not the MVA-BN (Jynneos) vaccine.The explanations "vaccine study" and "mpox virus challenge" were added to the first panel of Fig. 1 to clarify the study design.In the lower panel, the antibody functions were provided in more detail to avoid misunderstanding by the readers.The corrected figure is provided below.The main messages of this research highlight are not affected by these corrections.

Signal Transduction and Targeted TherapyVol. 9(1)
Universität Hamburg (DE), University Medical Center Hamburg-Eppendorf (DE), German Center for Infection Research (DE), Bernhard Nocht Institute for Tropical Medicine (DE)
Deutsche Forschungsgemeinschaft
Zero hunger
Openalex Percentile: Top 17%
Poxvirus research and outbreaks
1.47
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