α-klotho reduces susceptibility to osteoarthritis: evidence from cross-sectional studies and Mendelian randomization
In cross-sectional studies, α-klotho showed a nonlinear negative correlation with OA. MR analysis of outcomes was not identical to cross-sectional studies.
Authors
- Li Zhao (ORCID: https://orcid.org/0000-0001-8015-3055)
- Yibo Xu
- Qisheng Cheng
- Taotao Ren
- Yu Cui (ORCID: https://orcid.org/0000-0002-9608-8996)
- Bing Du (ORCID: https://orcid.org/0000-0001-5781-3713)
- Zhong Li
- Xinlin Nie
- Teng Ma
Institutions
- Jilin University (CN)
- Xi'an Honghui Hospital (CN)
- First Hospital of Jilin University (CN)
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2024-11-19
- DOI
- https://doi.org/10.3389/fendo.2024.1450472
- Citations
- 2
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.94