The Immune Epitope Database (IEDB): 2024 update
Over the past 20 years, the Immune Epitope Database (IEDB, iedb.org) has established itself as the foremost resource for immune epitope data. The IEDB catalogs published epitopes and their contextual experimental data in a freely searchable public resource. The IEDB team manually curates data from the literature into a structured format and spans infectious, allergic, autoimmune, and transplant diseases. Here, we describe the enhancements made since our 2018 paper, capturing user-directed updates to the search interface, advanced data exports, increases in data quality, and improved interoperability across related resources. As we look forward to the next 20 years, we are confident in our ability to meet the needs of our users and to contribute to the broader field of data standardization.
Authors
- Marcus Ennis (ORCID: https://orcid.org/0000-0002-6580-6297)
- Laura Zarebski
- Darren A. Natale (ORCID: https://orcid.org/0000-0001-5809-9523)
- Jason R Cantrell
- James A. Overton (ORCID: https://orcid.org/0000-0001-5139-5557)
- Alessandro Sette (ORCID: https://orcid.org/0000-0001-7013-2250)
- Nina Blazeska (ORCID: https://orcid.org/0000-0002-6604-0019)
- Brian Reardon (ORCID: https://orcid.org/0000-0002-6407-3255)
- Bjoern Peters (ORCID: https://orcid.org/0000-0002-8457-6693)
- Daniel Marrama (ORCID: https://orcid.org/0000-0001-5821-6857)
- Sara L. Coleman (ORCID: https://orcid.org/0000-0003-4680-4285)
- Jarjapu Mahita
- Catriona Macfarlane (ORCID: https://orcid.org/0000-0002-4733-5356)
- Deborah A. Shackelford
- Jason Greenbaum (ORCID: https://orcid.org/0000-0002-1381-0390)
- Matthew Busse
- Caitlin Sedwick (ORCID: https://orcid.org/0000-0001-9984-047X)
- Randi Vita (ORCID: https://orcid.org/0000-0001-8957-7612)
- Sebastian Duesing
- L S Zalman
- Jason W. Bennett (ORCID: https://orcid.org/0000-0001-5879-2037)
- Daniel K Wheeler
- Kenneth Chun‐Ho Chan
- Sandra Fitzpatrick
- Marcus Fabiano de Almeida Mendes (ORCID: https://orcid.org/0000-0002-2183-0121)
- Gabriele Foos
- Lindy Edwards
Institutions
- Leidos (United States) (US)
- La Jolla Institute for Immunology (US)
- Georgetown University (US)
- Georgetown University Medical Center (US)
- University of California San Diego (US)
- Arconic (United States) (US)
Publication Details
- Journal
- Nucleic Acids Research
- Published
- 2024-11-18
- DOI
- https://doi.org/10.1093/nar/gkae1092
- Citations
- 142
- Primary Topic
- vaccines and immunoinformatics approaches
- Type
- article
- Field-Weighted Citation Impact
- 33.20
Funders
- National Institutes of Health