Dipeptide alanine-glutamine ameliorates retinal neurodegeneration in an STZ-induced rat model
Ala-Gln ameliorates retinal neurodegeneration by reducing inflammation and enhancing glucose metabolism and mitochondrial function in DR. Therefore, manipulation of metabolism by Ala-Gln may be a novel therapeutic avenue for retinal neurodegeneration in DR.
Authors
- Zuguo Liu (ORCID: https://orcid.org/0000-0002-1737-5736)
- Yuan Xu (ORCID: https://orcid.org/0000-0003-2247-2845)
- Mingyan Wei
- Rongrong Zong
- Qian Chen (ORCID: https://orcid.org/0000-0002-3011-3722)
- Xiang Lin (ORCID: https://orcid.org/0009-0003-5331-8872)
- Yuhan Zhang (ORCID: https://orcid.org/0000-0002-2768-3900)
- Shiying Li (ORCID: https://orcid.org/0000-0003-0666-7634)
- Wensheng Chen (ORCID: https://orcid.org/0000-0002-2853-8422)
- Xin Wang (ORCID: https://orcid.org/0000-0003-0235-4913)
Institutions
- Xiamen University (CN)
- First Affiliated Hospital of Xiamen University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-11-19
- DOI
- https://doi.org/10.3389/fphar.2024.1490443
- Citations
- 1
- Primary Topic
- Amino Acid Enzymes and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.29
Funders
- Natural Science Foundation of Fujian Province
- Xiamen University