Stimulation of microneedles alleviates pathology of Parkinson’s disease in mice by regulating the CD4+/CD8+ cells from the periphery to the brain
Overall, our results suggest that the attachment of MPs to GB20 and GB34 is a new method to effectively improve the pathology of PD by restoring peripheral and brain immune function.
Authors
- Sookie La
- Do Hyeon Jeong
- Myung Sook Oh (ORCID: https://orcid.org/0000-0001-8189-4066)
- In Gyoung Ju (ORCID: https://orcid.org/0000-0001-9551-7528)
- Yujin Choi (ORCID: https://orcid.org/0000-0001-5257-2340)
- Chang-Su Na (ORCID: https://orcid.org/0000-0001-5478-649X)
- Jin Hee Kim (ORCID: https://orcid.org/0000-0003-4980-6331)
- Hanbyeol Lee
- Hi-Joon Park
- Jin Se Kim (ORCID: https://orcid.org/0009-0007-0471-9521)
- Na Young Yoo
Institutions
- Dongshin University (KR)
- Kyung Hee University (KR)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-11-19
- DOI
- https://doi.org/10.3389/fimmu.2024.1454102
- Citations
- 5
- Primary Topic
- Advancements in Transdermal Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 1.04
Funders
- National Research Foundation
- National Research Foundation of Korea