Neutralizing Activity and T-Cell Responses Against Wild Type SARS-CoV-2 Virus and Omicron BA.5 Variant After Ancestral SARS-CoV-2 Vaccine Booster Dose in PLWH Receiving ART Based on CD4 T-Cell Count
HCDR demonstrated robust humoral and cell-mediated immune responses after a booster dose of ancestral SARS-CoV-2 vaccine, whereas LCDR showed diminished immune responses against WT virus and more impaired cross-neutralization against omicron BA.5 strain.
Authors
- Na‐Young Ha (ORCID: https://orcid.org/0000-0003-3358-2548)
- C. Park (ORCID: https://orcid.org/0000-0001-8185-2384)
- H. J. Kim
- Shinhye Cheon (ORCID: https://orcid.org/0000-0002-1783-121X)
- Mi-Yeong An
- Sukyoung Jung (ORCID: https://orcid.org/0000-0001-9200-2158)
- Hyeon Nam (ORCID: https://orcid.org/0000-0002-9337-8859)
- M S Kim (ORCID: https://orcid.org/0009-0008-2918-978X)
- Jae Won Yoon (ORCID: https://orcid.org/0000-0003-1316-7136)
- June-Woo Lee (ORCID: https://orcid.org/0000-0002-2923-5597)
- Hyeongseok Jeong (ORCID: https://orcid.org/0000-0002-4539-079X)
- Kim Ys (ORCID: https://orcid.org/0000-0003-1142-5488)
- Ah‐Ra Kim (ORCID: https://orcid.org/0000-0001-5610-3787)
- Jae-Bung Choe (ORCID: https://orcid.org/0009-0001-1274-2197)
Institutions
- International Vaccine Institute (KR)
- Chungnam National University (KR)
- CHA Vaccine Institute (South Korea) (KR)
- Korea Institute for Health and Social Affairs (KR)
- Chungnam National University Hospital (KR)
Publication Details
- Journal
- Journal of Korean Medical Science
- Published
- 2024-11-19
- DOI
- https://doi.org/10.3346/jkms.2025.40.e28
- Citations
- 2
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.78
Funders
- National Research Foundation
- National Research Foundation of Korea
- Korea National Institute of Health