Temporal atrophy together with verbal encoding impairment is highly predictive for cognitive decline in typical Alzheimer’s dementia – a retrospective follow-up study
Our results show that temporal atrophy together with deficits in the encoding of verbal material, rather than in immediate or delayed recall, is highly predictive for rapid cognitive decline in patients with mild to moderate amnestic/typical ADD. These findings point to the relevance of combining detailed cognitive and automated structural imaging analyses to predict clinical progression in patients with ADD.
Authors
- Michaela Defrancesco (ORCID: https://orcid.org/0000-0001-9613-9485)
- Timo Schurr (ORCID: https://orcid.org/0000-0002-6757-7862)
- Elke R. Gizewski (ORCID: https://orcid.org/0000-0001-6859-8377)
- Alex Hofer (ORCID: https://orcid.org/0000-0002-5834-4258)
- Malik Galijašević (ORCID: https://orcid.org/0000-0001-6577-0784)
- Stephanie Mangesius (ORCID: https://orcid.org/0000-0001-5790-2724)
- Noora Tuovinen (ORCID: https://orcid.org/0000-0002-8835-5281)
- Ruth Steiger (ORCID: https://orcid.org/0000-0002-6905-9575)
- Burak Doganyigit
Institutions
- Innsbruck Medical University (AT)
- Universität Innsbruck (AT)
Publication Details
- Journal
- Frontiers in Psychiatry
- Published
- 2024-11-19
- DOI
- https://doi.org/10.3389/fpsyt.2024.1485620
- Citations
- 1
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.39