Research progress on the relationship between gastroesophageal reflux disease and sarcopenia

Abstract. With the advancement of population aging, it is increasingly vital to focus on the health conditions of the elderly. Sarcopenia is a condition characterized by gradual and systemic loss of skeletal muscle that may result in various outcomes, such as vulnerability, injuries and metabolic disorders, its impact on the lives of the elderly cant be ignored. Non-erosive reflux disease (NERD) is the most prevalent phenotype of gastroesophageal reflux disease (GERD), a major clinical gastrointestinal illness. Therefore, this article provides an overview of the definition, diagnosis, epidemiology, pathophysiology, and treatment of GERD and sarcopenia, with the intention of offering fresh viewpoints to improve the elderlys quality of life.