Efgartigimod treatment in patients with anti-MuSK-positive myasthenia gravis in exacerbation

This retrospective real-world study demonstrates the effectiveness and safety of efgartigimod in these four MuSK-Ab-positive, female Asian patients with exacerbation of MG, as well as in patients experiencing MC. It is important to note that efgartigimod should not be viewed as a substitute for foundational immunotherapy; rather, it is intended as a rescue treatment during exacerbations and as an adjunctive therapy in the context of long-term immunotherapy. This non-invasive approach has the potential to become another treatment option for MuSK-Ab-positive MG patients.

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Publication Details

Journal
Frontiers in Neurology
Published
2024-11-19
DOI
https://doi.org/10.3389/fneur.2024.1486659
Citations
8
Primary Topic
Myasthenia Gravis and Thymoma
Type
article
Field-Weighted Citation Impact
2.95

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article

Efgartigimod treatment in patients with anti-MuSK-positive myasthenia gravis in exacerbation

Xiaofei Sun, Feng Li, Hongyan Zhou, Huiyu Feng et al.
8 citations
Frontiers in Neurology
Myasthenia Gravis and Thymoma
2.95
article

Efgartigimod treatment in patients with anti-MuSK-positive myasthenia gravis in exacerbation

Xiaofei Sun, Feng Li, Hongyan Zhou, Huiyu Feng, Cunzhou Shen, Haiyan Wang, Jiaxin Chen, Fu‐Dong Shi, Jiezhen Feng, Rong Lai
article en
8 citations

Abstract

This retrospective real-world study demonstrates the effectiveness and safety of efgartigimod in these four MuSK-Ab-positive, female Asian patients with exacerbation of MG, as well as in patients experiencing MC. It is important to note that efgartigimod should not be viewed as a substitute for foundational immunotherapy; rather, it is intended as a rescue treatment during exacerbations and as an adjunctive therapy in the context of long-term immunotherapy. This non-invasive approach has the potential to become another treatment option for MuSK-Ab-positive MG patients.

Frontiers in NeurologyVol. 15
Sun Yat-sen University (CN), The First Affiliated Hospital, Sun Yat-sen University (CN)
National Natural Science Foundation of China, Natural Science Foundation of Guangdong Province
Good health and well-being
Openalex Percentile: Top 8%
Myasthenia Gravis and Thymoma
2.95
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