Research progress of curcumin and its nanodelivery system in anti-tumor field

Abstract. The focus of attention these days is on cancer prevention and treatment, as it is the second leading cause of death worldwide and its incidence continues to rise year. Due to its interactions with different cells and molecules, curcumin, a polyphenol natural substance derived from the turmeric plant, has numerous important applications in malignant disorders. Curcumin has demonstrated a high usage value and important benefits in the treatment of tumors; however, it has certain drawbacks, including low solubility, poor targeting, fast metabolism, and poor stability. The goal of this article is to enhance curcumins bioavailability and enhance the therapeutic impact of various tumor illnesses by means of a cooperative nano-drug delivery system involving chemotherapeutic medicines and curcumin.