Research progress of paclitaxel in the field of antitumor

Abstract. Cancer is the second leading cause of human death globally, and its incidence is still increasing year by year. How to prevent and treat cancer is currently the focus of attention. Paclitaxel is a natural anti-tumor drug that has multiple important applications in tumor diseases due to its interactions with various cells and molecules. Although paclitaxel has shown high utility value and significant advantages in tumor treatment, it has limitations such as low solubility, fast metabolism, and poor targeting. This article focuses on the mechanism of action and drug resistance of paclitaxel in anti-tumor applications, as well as the research progress in the treatment of various tumor diseases.