Altered Neural Processing of Interoception in Patients With Functional Neurological Disorder: A Task-Based fMRI Study
This study identified state and trait interoceptive disruptions in FND patients. Convergent between- and within-group findings contextualize the pathophysiological role of cingulo-insular (salience network) areas across the spectrum of functional seizures and functional movement disorder. These findings provide a starting point for the future development of comprehensive neurophysiological assessments of interoception for FND patients, features that also warrant research as potential prognostic and monitoring biomarkers.
Authors
- Petr Sojka (ORCID: https://orcid.org/0000-0002-7594-7093)
- Sahib S. Khalsa (ORCID: https://orcid.org/0000-0003-2124-8585)
- Ibai Díez (ORCID: https://orcid.org/0000-0001-5769-0178)
- David L. Perez (ORCID: https://orcid.org/0000-0003-2721-583X)
- Tereza Serranová (ORCID: https://orcid.org/0000-0001-6525-3971)
Institutions
- Allen Institute for Brain Science (US)
- Harvard University (US)
- Massachusetts General Hospital (US)
- Athinoula A. Martinos Center for Biomedical Imaging (US)
Publication Details
- Journal
- Journal of Neuropsychiatry
- Published
- 2024-11-19
- DOI
- https://doi.org/10.1176/appi.neuropsych.20240070
- Citations
- 14
- Primary Topic
- Psychosomatic Disorders and Their Treatments
- Type
- article
- Field-Weighted Citation Impact
- 5.40