PARATHYROID ADENOMA AND ITS UNUSUAL PRESENTATION: A CASE OF NECROTISING PANCREATITIS

Primary hyperparathyroidism (PHPT), often caused by a parathyroid adenoma, is a rare but important cause of hypercalcemia. Though PHPT typically presents with symptoms of bone pain, kidney stones, and gastrointestinal disturbances, it can occasionally lead to acute pancreatitis. Hypercalcemia-induced pancreatitis, while uncommon, presents a diagnostic challenge due to its non-specific symptoms and overlapping causes. We report the case of a 60- year-old female who presented with persistent epigastric pain ,vomiting and loss of apetite for over two months .She was diagnosed to have acute on chronic necrotising pancreatitis with persistent and worsening hypercalcemia ,with elevated serum intact parathyroid hormone levels (iPTH) which was diagnosed to be secondary to Parathyroid adenoma with the help of ultrasound neck and Sestamibi scan. Our objective is to highlight how crucial it is to take PHPT into account in patients with pancreatitis, without additional risk factors ,especially with persistent or worsening hypercalcemia and the effective role of parathyroidectomy in clinical resolution of such patients.

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Publication Details

Journal
PARIPEX INDIAN JOURNAL OF RESEARCH
Published
2024-10-15
DOI
https://doi.org/10.36106/paripex/3708137
Primary Topic
Pancreatitis Pathology and Treatment
Type
article
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article

PARATHYROID ADENOMA AND ITS UNUSUAL PRESENTATION: A CASE OF NECROTISING PANCREATITIS

Sowmya Gopalan, T. Suresh
PARIPEX INDIAN JOURNAL OF RESEARCH
Pancreatitis Pathology and Treatment
article

PARATHYROID ADENOMA AND ITS UNUSUAL PRESENTATION: A CASE OF NECROTISING PANCREATITIS

Sowmya Gopalan, T. Suresh
article en

Abstract

Primary hyperparathyroidism (PHPT), often caused by a parathyroid adenoma, is a rare but important cause of hypercalcemia. Though PHPT typically presents with symptoms of bone pain, kidney stones, and gastrointestinal disturbances, it can occasionally lead to acute pancreatitis. Hypercalcemia-induced pancreatitis, while uncommon, presents a diagnostic challenge due to its non-specific symptoms and overlapping causes. We report the case of a 60- year-old female who presented with persistent epigastric pain ,vomiting and loss of apetite for over two months .She was diagnosed to have acute on chronic necrotising pancreatitis with persistent and worsening hypercalcemia ,with elevated serum intact parathyroid hormone levels (iPTH) which was diagnosed to be secondary to Parathyroid adenoma with the help of ultrasound neck and Sestamibi scan. Our objective is to highlight how crucial it is to take PHPT into account in patients with pancreatitis, without additional risk factors ,especially with persistent or worsening hypercalcemia and the effective role of parathyroidectomy in clinical resolution of such patients.

PARIPEX INDIAN JOURNAL OF RESEARCH
Sri Ramachandra Institute of Higher Education and Research (IN)
Openalex Percentile: Top 61%
Pancreatitis Pathology and Treatment
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