Positron emission tomography harmonization in the Alzheimer's Disease Neuroimaging Initiative: A scalable and rigorous approach to multisite amyloid and tau quantification
Quantitative results from ADNI Aβ and tau PET data are generated using a rigorous, scalable image processing pipeline This pipeline has been applied to PET data from several other large, multisite studies and trials Quantitative outcomes are harmonizable across studies and are shared with the scientific community.
Authors
- Clifford R. Jack (ORCID: https://orcid.org/0000-0001-7916-622X)
- Alice Murphy
- Charles DeCarli
- Prashanthi Vemuri (ORCID: https://orcid.org/0000-0003-4286-0589)
- Christopher G. Schwarz (ORCID: https://orcid.org/0000-0002-1466-8357)
- William J. Jagust (ORCID: https://orcid.org/0000-0002-4458-113X)
- Suzanne L. Baker (ORCID: https://orcid.org/0000-0003-0209-3127)
- JiaQie Lee
- Theresa M. Harrison (ORCID: https://orcid.org/0000-0002-2036-3496)
- Robert A. Koeppe (ORCID: https://orcid.org/0000-0002-9514-5311)
- Tyler J. Ward (ORCID: https://orcid.org/0000-0002-4681-8137)
- Martin S. Boswell
- Trevor Chadwick
- Susan M. Landau
- Jacinda Taggett
Institutions
- Mayo Clinic (US)
- Lawrence Berkeley National Laboratory (US)
- University of Michigan (US)
- University of California, Davis (US)
- University of California, Berkeley (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-11-19
- DOI
- https://doi.org/10.1002/alz.14378
- Citations
- 28
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 10.80
Funders
- Alzheimer's Association
- Alzheimer's Disease Neuroimaging Initiative
- Takeda Pharmaceutical Company
- National Institutes of Health
- National Institute on Aging
- National Institute of Biomedical Imaging and Bioengineering