Kallikrein-Related Peptidase 6 Contributes to Murine Intestinal Tumorigenesis Driven by a Mutant Adenomatous polyposis coli Gene
These findings demonstrate the oncogenic role of KLK6 in the mutant <i>Apc</i>-mediated intestinal tumorigenesis and suggest the utility of KLK6 for early diagnosis of colorectal tumors.
Authors
- Dalila Darmoul (ORCID: https://orcid.org/0000-0002-1206-0655)
- Hwudaurw Chen
- Natalia A. Ignatenko (ORCID: https://orcid.org/0000-0002-8096-1340)
- Jennifer K. Barton (ORCID: https://orcid.org/0000-0003-4897-9361)
- Haiyan Cui (ORCID: https://orcid.org/0000-0003-4969-4835)
- Teodora Georgieva (ORCID: https://orcid.org/0000-0002-8632-8714)
- Photini F. Rice (ORCID: https://orcid.org/0000-0001-7100-4023)
- David G. Besselsen (ORCID: https://orcid.org/0000-0001-5890-0501)
Institutions
- Centre National de la Recherche Scientifique (FR)
- University of Arizona (US)
- Inserm (FR)
- Sorbonne Université (FR)
- Institut de Biologie Paris-Seine (FR)
- Adaptation Biologique et Vieillissement (FR)
- University of Arizona Cancer Center
Publication Details
- Journal
- Cancers
- Published
- 2024-11-15
- DOI
- https://doi.org/10.3390/cancers16223842
- Primary Topic
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Arizona Cancer Center
- University of Texas MD Anderson Cancer Center