Catalytic enantioselective and site-specific Friedel–Crafts alkylation of 4-aminoindoles with β,γ-alkynyl-α-ketoimines for the synthesis of C7-functionalized indoles
CPA-catalyzed asymmetric Friedel–Crafts alkylation of 4-aminoindoles with ketoimines enables the synthesis of chiral C7-functionalized indoles.
Authors
- Xue-Man Zhang
- Jian‐Qiang Zhao (ORCID: https://orcid.org/0000-0002-4444-9630)
- Juan Liao (ORCID: https://orcid.org/0000-0002-0005-5728)
- Zhen‐Hua Wang (ORCID: https://orcid.org/0000-0002-0603-707X)
- Wei‐Cheng Yuan (ORCID: https://orcid.org/0000-0003-4850-8981)
- Yanping Zhang (ORCID: https://orcid.org/0000-0002-1680-7592)
- Lei Yang (ORCID: https://orcid.org/0000-0002-5226-2083)
- Yong You (ORCID: https://orcid.org/0000-0002-4689-0235)
Institutions
- Chinese Academy of Sciences (CN)
- Chengdu Organic Chemicals (China) (CN)
- Chengdu University (CN)
- University of Chinese Academy of Sciences (CN)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2024-11-19
- DOI
- https://doi.org/10.1039/d4qo01856g
- Citations
- 9
- Primary Topic
- Asymmetric Hydrogenation and Catalysis
- Type
- article
- Field-Weighted Citation Impact
- 1.43