Statin‐associated regulation of hepatic <i>PNPLA3</i> in patients without known liver disease
Collectively, these observations suggest statin-associated regulation of PNPLA3 and DNL in liver. The potential interaction between PNPLA3 genotype and metabolic status should be considered in future studies in the context of statin therapy for MASLD.
Authors
- Giuseppe Danilo Norata (ORCID: https://orcid.org/0000-0002-6081-1257)
- Laura Tarnawski (ORCID: https://orcid.org/0000-0001-7993-0232)
- Vladimir S. Shavva (ORCID: https://orcid.org/0000-0002-5080-8636)
- Stephen Malin (ORCID: https://orcid.org/0000-0001-7723-9579)
- Hanna M. Björck (ORCID: https://orcid.org/0000-0002-9155-3609)
- Per Eriksson (ORCID: https://orcid.org/0000-0002-5635-2692)
- Frank ter Borg (ORCID: https://orcid.org/0000-0003-4396-4996)
- Anders Franco‐Cereceda (ORCID: https://orcid.org/0000-0002-3427-9455)
- Paolo Parini (ORCID: https://orcid.org/0000-0002-6541-8542)
- Peder S. Olofsson (ORCID: https://orcid.org/0000-0003-3473-5948)
- Peter Saliba‐Gustafsson (ORCID: https://orcid.org/0000-0002-7807-9009)
- Matteo Pedrelli (ORCID: https://orcid.org/0000-0003-0771-0569)
- Ahmed Osman (ORCID: https://orcid.org/0000-0002-2854-2552)
- Wanmin Dai
- Otto Bergman (ORCID: https://orcid.org/0000-0003-4323-8150)
- Ting Liu (ORCID: https://orcid.org/0000-0002-5301-6562)
- Viggo V. Olofsson
- Christian Simini
Institutions
- Feinstein Institute for Medical Research (US)
- Karolinska University Hospital (SE)
- University of Milan (IT)
- Karolinska Institutet (SE)
- Arabian Gulf University (BH)
Publication Details
- Journal
- Journal of Internal Medicine
- Published
- 2024-11-19
- DOI
- https://doi.org/10.1111/joim.20032
- Citations
- 2
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.77
Funders
- Hjärt-Lungfonden
- Novo Nordisk
- Vetenskapsrådet