Network Meta-Analysis and Trial Sequential Analysis of Randomised Controlled Trials Comparing Robotic, Laparoscopic, and Open Pancreatoduodenectomy
The current RCT evidence suggests potential better outcomes in LPD in comparison with RPD and OPD. However, few studies demonstrated robust statistical significance in outcome measures, suggesting an underpowered evidence base and possible selection bias. Hence, with current equivocal data, there is a need for ongoing RCTs to validate the role of minimally invasive approaches in PD.
Authors
- Matthew McGuinness (ORCID: https://orcid.org/0000-0002-0842-5922)
- Mohammad Abu Hilal (ORCID: https://orcid.org/0000-0002-3162-4639)
- Marc G. Besselink (ORCID: https://orcid.org/0000-0003-2650-9350)
- Kjetil Søreide (ORCID: https://orcid.org/0000-0001-7594-4354)
- Sanjay Pandanaboyana (ORCID: https://orcid.org/0000-0003-3099-2197)
- Giovanni Marchegiani (ORCID: https://orcid.org/0000-0002-6824-4533)
- Nejo Joseph (ORCID: https://orcid.org/0000-0003-2872-0977)
- Jas Samra
- James Lucocq (ORCID: https://orcid.org/0000-0002-6979-7818)
- Samuel J Tingle (ORCID: https://orcid.org/0000-0001-5529-7815)
- Chris Varghese (ORCID: https://orcid.org/0000-0001-7369-8639)
- Steve White
Institutions
- NHS Lothian (GB)
- University of Padua (IT)
- University of Auckland (NZ)
- Royal North Shore Hospital (AU)
- Stavanger University Hospital (NO)
- Freeman Hospital (GB)
- North Shore Hospital (NZ)
- University Hospital Southampton NHS Foundation Trust (GB)
- Newcastle University (GB)
Publication Details
- Journal
- Annals of Surgery Open
- Published
- 2024-11-19
- DOI
- https://doi.org/10.1097/as9.0000000000000507
- Citations
- 7
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 1.98
Funders
- Medical Research Council