Estimation of PfRh5-based vaccine efficacy in asymptomatic Plasmodium falciparum patients from high-endemic areas of Tanzania using genetic and antigenicity variation screening

These findings underscore the need for future PfRh5-based vaccines to consider for increasing genetic variation and geographical differences in humoral immune responses.

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Publication Details

Journal
Frontiers in Immunology
Published
2024-11-18
DOI
https://doi.org/10.3389/fimmu.2024.1495513
Citations
6
Primary Topic
Malaria Research and Control
Type
article
Field-Weighted Citation Impact
3.26

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article

Estimation of PfRh5-based vaccine efficacy in asymptomatic Plasmodium falciparum patients from high-endemic areas of Tanzania using genetic and antigenicity variation screening

Yeonkyung Kim, Alphaxard Manjurano, Se Jin Lee, Md Atique Ahmed et al.
6 citations
Frontiers in Immunology
Malaria Research and Control
3.26
article

Estimation of PfRh5-based vaccine efficacy in asymptomatic Plasmodium falciparum patients from high-endemic areas of Tanzania using genetic and antigenicity variation screening

Yeonkyung Kim, Alphaxard Manjurano, Se Jin Lee, Md Atique Ahmed, Jin-Hee Han, Wanjoo Chun, Fauzi Muh, Bo-Eun Kwon, Soo-Ung Lee, Winifrida Kidima, Hojong Jun, Wang-Jong Lee, Jim Todd, Sunghun Na, Ernest Mazigo, Johnsy Mary Louis, Won Sun Park, Eun‐Taek Han, Feng Lu, Min Hong, Tae-Hyung Kwon, Fadhila Fitriana, Jadidan Hada Syahada, Jin Seok Heo, Joon-Hee Han
article en
6 citations

Abstract

These findings underscore the need for future PfRh5-based vaccines to consider for increasing genetic variation and geographical differences in humoral immune responses.

Frontiers in ImmunologyVol. 15
Diponegoro University (ID), Kangwon National University (KR), University of Dar es Salaam (TZ), Catholic University of Health and Allied Sciences (TZ), Indian Council of Medical Research (IN), London School of Hygiene & Tropical Medicine (GB), Regional Medical Research Centre (IN), Kangwon National University Hospital (KR), Jeonnam Bioindustry Foundation (KR), National Institute for Medical Research (TZ), Yangzhou University (CN)
National Research Foundation, Korea Health Industry Development Institute, National Research Foundation of Korea, Ministry of Education, India
Good health and well-being
Openalex Percentile: Top 7%
Malaria Research and Control
3.26
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