Case report: Triple-negative breast cancer with low tumour-infiltrating lymphocytes infiltration and good prognosis: a case of Tall Cell Carcinoma with Reversed Polarity and review of the literature
TCCRP is a rare TNBC with inert biological behaviours and good prognosis. We found low infiltration of TILs in the pathological tissue of this case, which may be a characteristic of TCCRP, and the presence of Cancer-Associated Fibroblasts (CAF) in the interstitium of the tumour in this case may have suppressed the anti-tumour immunity to some extent, and further studies on the immune characteristics of the tumour microenvironment (TME) in TCCRP are needed.
Authors
- Junpeng Chen (ORCID: https://orcid.org/0000-0003-2307-6406)
- Xiaohua Pei (ORCID: https://orcid.org/0000-0003-3043-8874)
- Ajing Peng
- Shuoying Jiao
- Ruifu Chen
- Chunhua Luo
- Yingyi Fan
- Baoyong Lai (ORCID: https://orcid.org/0000-0002-9464-6245)
- Jiumei Shen
Institutions
- Union Hospital (HK)
- Beijing University of Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2024-11-18
- DOI
- https://doi.org/10.3389/fonc.2024.1455893
- Primary Topic
- Peptidase Inhibition and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Beijing University of Chinese Medicine