A COMPARTIVE ANALYSIS IN EASTERN PART OF UTTAR PRADESH ASSESSING THE SAFETY AND EFFICACY OF INTRAVENOUS IRON SUCROSE VS INTRAMUSCULAR IRON SORBITOL FOR IRON DEFICIENCY ANEMIA IN PREGNANT WOMEN

Background: Anemiais themostcommonlyhaematologicaldisorderinpregnancy.Anemiaisassociatedwith higher perinatal mortality and morbidity. In the developing countries like India more than two third pregnant womensufferfromanemiaoutofwhich95%ofcasesareduetoIrondeciencyanemia.Irondeciencyanemiaareduetopoornutrition and it is estimated to affect nearly two third of pregnant women in developing countries like India. Aim: To compare the safety and efcacyofintravenous ironsucrosewithintramuscularironsorbitolinpregnantwomenineasternpartofUttarpradesh.Objectives:To compare the safety of intravenous iron sucrose with intramuscular iron sorbitol. To compare efcacy of intravenous iron sucrose with intramuscular iron sorbitol. Material And Methods: 100 antenatal women attending outpatient department with haemoglobin 7- 9gm/dl will be recruited randomly and then they are divided into two groups different group of 50 each. To the 50 patients groupAiron sucrose is given and to 50 patients group B iron sorbitol is given. Then safety efcacy and adverse drug reaction with both the therapy were recorded. Result: Haemoglobin concentration raised signicantly in both the groups. The increase rise in haemoglobin level in Group A and Group B signicantly high in by the fourth week. But none of the group B case reached the target level of haemoglobin during this observation period. With iron sorbitol adverse event were common. However no serious adverse drug reactions were observed. Conclusion: Intravenous iron sucrose is found to be more safe and more efcacious and faster acting then intramuscular ironsorbitoltherapytotreatfortreatingmoderatetosevereanemiainpregnantwomen.