<i>β</i>-Defensin <i>versus</i> conventional markers of inflammation in periprosthetic joint infection: a retrospective study
The synovial <i>β</i>-defensin assay demonstrated greater sensitivity and specificity for the diagnosis of PJI compared to ESR, serum CRP and WBC. Therefore, <i>β</i>-defensin shows promise as a diagnostic marker for PJI. Simultaneous determination of all markers may increase diagnostic confidence.
Authors
- Yessica Zamudio‐Cuevas (ORCID: https://orcid.org/0000-0003-1751-3454)
- Ámbar López-Macay (ORCID: https://orcid.org/0000-0002-2916-7424)
- Ernesto Roldán-Valadéz (ORCID: https://orcid.org/0000-0002-7116-5289)
- Rafael Franco‐Cendejas (ORCID: https://orcid.org/0000-0003-1574-1138)
- Javier Fernández‐Torres (ORCID: https://orcid.org/0000-0002-7271-2862)
- Karina Martínez‐Flores (ORCID: https://orcid.org/0000-0003-0675-0227)
- Maria Guadalupe Martínez-Zavaleta (ORCID: https://orcid.org/0009-0008-5845-6146)
- Luis Esaú López-Jácome (ORCID: https://orcid.org/0000-0001-7387-0937)
- Graciela Rosas-Alquicira
Institutions
- Instituto Nacional de Rehabilitación (MX)
- Universidad Nacional Autónoma de México (MX)
Publication Details
- Journal
- PeerJ
- Published
- 2024-11-18
- DOI
- https://doi.org/10.7717/peerj.18560
- Citations
- 2
- Primary Topic
- Orthopedic Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.15