The Atypical Neural Processing of Reward in Bipolar Disorder

Abstract: There are still many unanswered questions regarding bipolar disorder among researchers. Understanding the characteristics of a particular area and neuroeconomics can aid in a more thorough examination of reward dysfunction and the reward process. Because changes in reward are undoubtedly one of the most prevalent signs of psychopathology in humans, researchers try to understand the prevalence of these diseases as well as the importance of reward in the manifestation of these conditions. Research indicates that different biological entities with comparable phenotypic symptoms make up bipolar illness. Finding the primary and secondary rewards connected to the functioning resting-state of bipolar illness patients' brain circuits is the goal of another investigation. On the other hand, using a reward task that begins with the expectation and consumption of rewarding and nonrewarding outcomes and progresses through fixation point, target, and outcome screen, researchers hope to better understand the connections between healthy individuals and BD patients' reward processing and striatal responses. This review can provide some suggestions to the development of prevention and intervention programs for individuals at risk of BD.