Study on the chemical stability of β-lactam antibiotics in concomitant simple suspensions with magnesium oxide
Amoxicillin and MgO should be independently suspended because of the chemical instability of amoxicillin. This study has also indicated there is a degradation risk after prolonged soaking. It should be noted that the poor water solubility of cefcapene pivoxil under alkaline conditions may affect the absorption process as well as tube passability.
Authors
- Kazuki Akira (ORCID: https://orcid.org/0000-0001-5344-0913)
- Ginjiro Kato (ORCID: https://orcid.org/0000-0003-1741-7243)
- Hidemichi Mitome (ORCID: https://orcid.org/0000-0002-5839-4781)
- Mamoru Tanaka (ORCID: https://orcid.org/0000-0001-8416-5774)
- Noriaki Hidaka (ORCID: https://orcid.org/0000-0002-3484-9809)
- Syu Takeda
Institutions
- Matsuyama University (JP)
- Ehime University Hospital (JP)
- Ehime University (JP)
Publication Details
- Journal
- Journal of Pharmaceutical Health Care and Sciences
- Published
- 2024-11-18
- DOI
- https://doi.org/10.1186/s40780-024-00396-0
- Citations
- 5
- Primary Topic
- Pharmacy and Medical Practices
- Type
- article
- Field-Weighted Citation Impact
- 2.33