Diagnostic Accuracy of Mammography for Breast Cancer Diagnosis, Taking Histopathology asStandard Investigation

Objective: To find out the exact accuracy of diagnosis of Mammography for females presented with breast lump.Study Design: A cross-sectional observational studyPlace and Duration of Study: Ward 3, Jinnah Postgraduate Medical Center, Karachi Pakistan, from Sep 2021 to Dec 2021.Methodology: Total 210 female patients above 35 years of age, with breast lump presented in outpatient department of Jinnah postgraduate Medical Centre enrolled in this study. Out of 210 patients, 80 patients were provisionally diagnosed as benign breast lump i-e BIRADS I, II and III, and 130 as malignant i-e BIRADS IV, V, and VI were included on the basis of Mammography done from Radiology department. Trucut biopsy of the breast lump of more than 2cm and excision biopsy of the lump less than 2cm was done. Final diagnosis of histopathological report compared with provisional diagnosis. Results were noted on Performa and analyzed.Results: A total of 210 patients were enrolled in the study on the basis of Mammography. Out of 210 patients, 130(61.9%) patients were considered as malignant and 80(38.1%) patients as benign lumps. Diagnostic accuracy of Mammography was 96.19%, taking histopathology as standard investigation. The sensitivity, specificity, positive predictive value, and negative predictive value, were 98.41%, 92.86%, 95.38%, and 97.50%, respectively.Conclusion: Mammography proved significantly diagnostic for carcinoma of breast.