Protective Potential of Sodium-Glucose Cotransporter 2 Inhibitors in Internal Medicine (Part 1)
Sodium-glucose cotransporter 2 inhibitors (SGLT2i) have emerged as a revolutionary class of drugs with far-reaching protective effects in multiple organs. The protective potential of SGLT2i is much broader than that of the classical concept of glucose control and consists of an entire conglomerate of associated pleiotropic effects. This study aims to provide a descriptive review of the pleiotropic therapeutic potential of SGLT2i. The first part of the literature review examined the use of SGLT2i in cardiology and nephrology. The use of SGLT2i represents an innovative approach to improving patients’ quality of life and course of heart failure and chronic kidney disease, regardless of left ventricular ejection fraction and type 2 diabetes.
Authors
- F. M. Khamidova (ORCID: https://orcid.org/0000-0001-6084-7025)
- L. A. Martemyanova (ORCID: https://orcid.org/0000-0003-0532-148X)
- Tamara R. Gevorgyan
- Nizal Sarrafzadegan (ORCID: https://orcid.org/0000-0002-6828-2169)
- Anahit Z. Aznauryan (ORCID: https://orcid.org/0000-0002-9642-7740)
- Anna R. Petrosyan
- Mohammad Sheibani (ORCID: https://orcid.org/0000-0003-2495-2957)
- Karmen Sahakyan (ORCID: https://orcid.org/0009-0002-0486-0844)
- Nana Pogosova (ORCID: https://orcid.org/0000-0002-4165-804X)
- О. И. Уразова (ORCID: https://orcid.org/0000-0002-9457-8879)
- А. И. Трофименко (ORCID: https://orcid.org/0000-0001-7140-0739)
- L. M. Sukiasyan (ORCID: https://orcid.org/0000-0001-7696-0639)
- Ashot Avagimyan (ORCID: https://orcid.org/0000-0002-5383-8355)
- Marina R. Tatoyan
- Evgenii E. Lysov (ORCID: https://orcid.org/0000-0002-9743-0394)
- Gayne Mkrtchyan
- Ruzanna Petrosyan (ORCID: https://orcid.org/0000-0001-6787-0893)
- Goharik L. Meltonyan
Institutions
- Isfahan University of Medical Sciences (IR)
- Peoples' Friendship University of Russia (RU)
- Iran University of Medical Sciences (IR)
- Kuban State Medical University (RU)
- Gomel State Medical University (BY)
- Siberian State Medical University (RU)
- Samarkand State Medical Institute (UZ)
- Lebanese American University (LB)
- Yerevan State Medical University (AM)
Publication Details
- Journal
- Innovative medicine of Kuban
- Published
- 2024-11-15
- DOI
- https://doi.org/10.35401/2541-9897-2024-9-4-126-135
- Citations
- 5
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.79