A case of penicillin-resistant group B <i>Streptococcus</i> isolated from a patient in the UK
We confirm the first identification of a PRGBS isolate amongst referrals to the UK's national reference laboratory. Substitutions in pbp1a, pbp2a, pbp2x and pbp2b were identified that likely developed in the face of long-term beta-lactam antibiotic use.
Authors
- Derren Ready (ORCID: https://orcid.org/0000-0003-4894-3641)
- Isabelle Potterill (ORCID: https://orcid.org/0009-0003-4598-9844)
- Rebecca Guy (ORCID: https://orcid.org/0000-0001-5500-5691)
- Antonia Scobie (ORCID: https://orcid.org/0000-0002-0941-9866)
- Simon Warren (ORCID: https://orcid.org/0000-0001-6857-6303)
- Emma McGuire (ORCID: https://orcid.org/0000-0001-7097-4116)
- Damien Mack (ORCID: https://orcid.org/0000-0001-6837-6467)
- Katie L. Hopkins (ORCID: https://orcid.org/0000-0001-7279-5322)
- Colin Stewart Brown (ORCID: https://orcid.org/0000-0003-4776-3403)
- Theresa Lamagni (ORCID: https://orcid.org/0000-0002-3965-8323)
- Rachel Pike (ORCID: https://orcid.org/0000-0002-2717-1446)
- Nicholas Ellaby (ORCID: https://orcid.org/0000-0001-6480-4452)
- J. Coelho
Institutions
- Royal Free London NHS Foundation Trust (GB)
- Royal National Orthopaedic Hospital (GB)
- Public Health England (GB)
- University of Bristol (GB)
- NIHR Imperial Biomedical Research Centre (GB)
- NIHR Bristol Biomedical Research Centre (GB)
- UK Health Security Agency (GB)
- University College London (GB)
- Imperial College London (GB)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2024-11-15
- DOI
- https://doi.org/10.1093/jac/dkae419
- Citations
- 17
- Primary Topic
- Neonatal and Maternal Infections
- Type
- article
- Field-Weighted Citation Impact
- 9.23