NEONATAL OUTCOMES IN INFANTS OF DIABETIC MOTHERS: FOCUS ON HYPOGLYCEMIA, RESPIRATORY DISTRESS SYNDROME AND MACROSOMIA

Background: Infants of diabetic mothers (IDMs) face heightened risks of various neonatal complications. This study evaluates the incidence of specific complications-macrosomia, hypoglycaemia, and neonatal respiratory distress syndrome (NRDS)-in this population. Methods: A cross-sectional observational study was conducted over 1.5 years at a tertiary hospital in Mumbai. We reviewed the medical records of infants born to mothers with diabetes (both pregestational and gestational). Data on the incidence of macrosomia (birth weight >4000 grams), hypoglycaemia (blood glucose <40 mg/dL), and NRDS (diagnosed based on clinical and radiographic criteria) were collected. Results: Among the 50 infants studied, 8% were diagnosed with macrosomia, 46% experienced hypoglycaemia, and 20% developed NRDS. The frequency of these complications was significantly higher in IDMs compared to the general neonatal population. Conclusion: This study reveals a high incidence of macrosomia, hypoglycaemia, and NRDS in IDMs, emphasizing the need for regular antenatal follow-up and strict glycaemic control throughout pregnancy. Enhanced monitoring and management strategies are essential to mitigate these risks and improve neonatal health outcomes.