TOXIC ALCOHOL POISONING: A CASE REPORT

During the COVID-19 pandemic, toxic alcohol poisoning, notably from methanol, has emerged as a significant concern due to increased consumption of illicit liquor amidst lockdown restrictions. We present a case of a middle-aged man who developed altered consciousness, metabolic acidosis, and shock two days after ingesting hospital spirit. Although initial qualitative tests only detected ethanol, subsequent MRI findings showed classical signs of methanol poisoning, including basal ganglia abnormalities. Prompt management with dialysis, ventilatory support, and adjunctive therapy successfully addressed the acute phase despite the patient remaining delirious for seven days. This case underscores the importance of considering methanol toxicity even in the absence of direct evidence, necessitating comprehensive diagnostic approaches. Awareness and incorporating point-of-care assessments such as arterial blood gas analysis and osmolar gap evaluation in suspected cases are crucial, especially in resource-limited settings. Recognizing unexplained high anion gap metabolic acidosis with a high osmolar gap and characteristic MRI findings can aid in the early diagnosis and management of toxic alcohol poisoning

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Publication Details

Journal
Asian Journal of Pharmaceutical and Clinical Research
Published
2024-11-07
DOI
https://doi.org/10.22159/ajpcr.2024v17i11.50744
Primary Topic
Poisoning and overdose treatments
Type
article
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article

TOXIC ALCOHOL POISONING: A CASE REPORT

A K Koshy, Stéphanie Thomas, ATHULYA G ASOKAN
Asian Journal of Pharmaceutical and Clinical Research
Poisoning and overdose treatments
article

TOXIC ALCOHOL POISONING: A CASE REPORT

A K Koshy, Stéphanie Thomas, ATHULYA G ASOKAN
article en

Abstract

During the COVID-19 pandemic, toxic alcohol poisoning, notably from methanol, has emerged as a significant concern due to increased consumption of illicit liquor amidst lockdown restrictions. We present a case of a middle-aged man who developed altered consciousness, metabolic acidosis, and shock two days after ingesting hospital spirit. Although initial qualitative tests only detected ethanol, subsequent MRI findings showed classical signs of methanol poisoning, including basal ganglia abnormalities. Prompt management with dialysis, ventilatory support, and adjunctive therapy successfully addressed the acute phase despite the patient remaining delirious for seven days. This case underscores the importance of considering methanol toxicity even in the absence of direct evidence, necessitating comprehensive diagnostic approaches. Awareness and incorporating point-of-care assessments such as arterial blood gas analysis and osmolar gap evaluation in suspected cases are crucial, especially in resource-limited settings. Recognizing unexplained high anion gap metabolic acidosis with a high osmolar gap and characteristic MRI findings can aid in the early diagnosis and management of toxic alcohol poisoning

Asian Journal of Pharmaceutical and Clinical Research
Government Medical College (IN), Jubilee Mission Medical College and Research Institute (IN), Pushpagiri Medical College (IN)
Good health and well-being
Openalex Percentile: Top 63%
Poisoning and overdose treatments
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TOXIC ALCOHOL POISONING: A CASE REPORT — A K Koshy, Stéphanie Thomas, et al. · Asian Journal of Pharmaceutical and Clinical Research (2024) | TGRS Research Map | TGRS