BLOODSTREAM INFECTIONS AND ITS ANTIBIOGRAM OF INTENSIVE CARE UNITS IN A TERTIARY CARE HOSPITAL OF CENTRAL INDIA

Objective: To perform bacteriological analysis and to study drug susceptibility patterns of isolates from bloodstream infections. Methods: This retrospective study was conducted in the microbiology department of NSCB Medical College, Jabalpur, spanning from July 2023 to December 2023. The study included blood culture samples from all adult intensive care unit patients of the medical college. Blood samples were collected with aseptic guidelines and cultured for 7 days. Growths were identified using standard biochemical tests and subjected to sensitivity testing according to Modified Kirby-Bauer’s disk diffusion method. Data for the source of blood collection and duration of incubation were noted and compared. Results: A total of 100 (21.7%) pathogens were isolated from 460 bacteremia suspect patient blood specimens. Pseudomonas spp. Were predominant organisms recovered followed by Klebsiella spp. and Staphylococcus aureus, coagulase-negative staphylococci, and Acinetobacter spp. were the primary pathogens isolated. Carbapenems, glycopeptides, and aminoglycosides were the most effective drugs for treating bacteremia. Conclusions: Early diagnosis and proper antimicrobial therapy lead to successful treatment of sepsis and decreased morbidity and mortality. Antibiogram of a particular area helps in rationalizing verified treatment strategies.