Cover Feature: Isonitrile Photochemistry: A Functional Group Class Coming in from the Cold (Chem. Eur. J. 64/2024)

Despite being an important class of compounds with broad applications in organic synthesis, isonitriles have often been neglected due to concerns about their unpleasant odor, stability, and toxicity. Recently, the potential to exploit their stereoelectronic properties in light-triggered synthetic methods leading to unique reactivity patterns has sparked renewed interest, allowing them to come in from the cold. More information can be found in the Concept by M. Giustiniano (DOI: 10.1002/chem.202402350). Artwork created by Gennaro Maddaloni.