[Analysis of the epidemic characteristics and treatment outcomes of rifampicin-resistant pulmonary tuberculosis in Yangzhou City from 2012 to 2020].

Information on patients with rifampicin-resistant pulmonary tuberculosis (RR-PTB) in Yangzhou City from 2012 to 2020 was obtained from the Information System of the Chinese Center for Disease Control and Prevention. The epidemic characteristics of RR-PTB patients were analyzed by using <i>χ</i><sup>2</sup> test. The average annual registered incidence rate of RR-PTB patients in Yangzhou City from 2012 to 2020 was 0.57/100 000, and the difference between the registered incidence rates in each year was statistically significant (<i>χ</i><sup>2</sup>=29.326, <i>P</i><0.001). The proportion of re-treated patients (64.8%) was higher than that of newly treated patients (35.2%, <i>χ</i><sup>2</sup>=50.593, <i>P</i><0.001). The registered incidence rate in males (0.91/100 000) was higher than that in females (0.24/100 000, <i>χ</i><sup>2</sup>=80.566, <i>P</i><0.001). The age distribution showed that the highest incidence rate was in the age group≥60 years (0.96/100 000) and the lowest was in the age group 0-<45 years (0.31/100 000, <i>χ</i><sup>2</sup>=55.853, <i>P</i><0.001). From 2012 to 2020, Baoying County had the largest number of registered RR-PTB patients (44 cases), and its registered incidence rate (0.64/100 000) was only lower than that of Guangling District (0.98/100 000). The registered incidence rate of RR-PTB patients in Baoying County during 2016-2020 also increased significantly compared to 2012-2015 (<i>P</i>=0.001). Logistic regression was used to analyze the factors related to the treatment outcome of RR-PTB patients. The results showed that patients aged≥60 years and those classified as the re-treatment were risk factors for successful treatment of RR-PTB patients (<i>P</i><0.05). In summary, males, people aged≥60 years, patients classified as the re-treatment, and residents of Baoying County should be the key populations for RR-PTB epidemic prevention and control in Yangzhou City.

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Publication Details

Journal
PubMed
Published
2024-11-06
DOI
https://doi.org/10.3760/cma.j.cn112150-20240102-00003
Primary Topic
Tuberculosis Research and Epidemiology
Type
article
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[Analysis of the epidemic characteristics and treatment outcomes of rifampicin-resistant pulmonary tuberculosis in Yangzhou City from 2012 to 2020].

Limei Zhu, Bo Chen, J C Li, Lingling Wang et al.
PubMed
Tuberculosis Research and Epidemiology
article

[Analysis of the epidemic characteristics and treatment outcomes of rifampicin-resistant pulmonary tuberculosis in Yangzhou City from 2012 to 2020].

Limei Zhu, Bo Chen, J C Li, Lingling Wang, Heng Wang, Qinyu Zhao
article en

Abstract

Information on patients with rifampicin-resistant pulmonary tuberculosis (RR-PTB) in Yangzhou City from 2012 to 2020 was obtained from the Information System of the Chinese Center for Disease Control and Prevention. The epidemic characteristics of RR-PTB patients were analyzed by using <i>χ</i><sup>2</sup> test. The average annual registered incidence rate of RR-PTB patients in Yangzhou City from 2012 to 2020 was 0.57/100 000, and the difference between the registered incidence rates in each year was statistically significant (<i>χ</i><sup>2</sup>=29.326, <i>P</i><0.001). The proportion of re-treated patients (64.8%) was higher than that of newly treated patients (35.2%, <i>χ</i><sup>2</sup>=50.593, <i>P</i><0.001). The registered incidence rate in males (0.91/100 000) was higher than that in females (0.24/100 000, <i>χ</i><sup>2</sup>=80.566, <i>P</i><0.001). The age distribution showed that the highest incidence rate was in the age group≥60 years (0.96/100 000) and the lowest was in the age group 0-<45 years (0.31/100 000, <i>χ</i><sup>2</sup>=55.853, <i>P</i><0.001). From 2012 to 2020, Baoying County had the largest number of registered RR-PTB patients (44 cases), and its registered incidence rate (0.64/100 000) was only lower than that of Guangling District (0.98/100 000). The registered incidence rate of RR-PTB patients in Baoying County during 2016-2020 also increased significantly compared to 2012-2015 (<i>P</i>=0.001). Logistic regression was used to analyze the factors related to the treatment outcome of RR-PTB patients. The results showed that patients aged≥60 years and those classified as the re-treatment were risk factors for successful treatment of RR-PTB patients (<i>P</i><0.05). In summary, males, people aged≥60 years, patients classified as the re-treatment, and residents of Baoying County should be the key populations for RR-PTB epidemic prevention and control in Yangzhou City.

PubMedVol. 58(11)
Jiangsu Provincial Center for Disease Control and Prevention (CN), Nanjing Municipal Center for Disease Control And Prevention (CN), Yangzhou University (CN)
Tuberculosis Research and Epidemiology
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