[Analysis of the epidemic characteristics and treatment outcomes of rifampicin-resistant pulmonary tuberculosis in Yangzhou City from 2012 to 2020].
Information on patients with rifampicin-resistant pulmonary tuberculosis (RR-PTB) in Yangzhou City from 2012 to 2020 was obtained from the Information System of the Chinese Center for Disease Control and Prevention. The epidemic characteristics of RR-PTB patients were analyzed by using <i>χ</i><sup>2</sup> test. The average annual registered incidence rate of RR-PTB patients in Yangzhou City from 2012 to 2020 was 0.57/100 000, and the difference between the registered incidence rates in each year was statistically significant (<i>χ</i><sup>2</sup>=29.326, <i>P</i><0.001). The proportion of re-treated patients (64.8%) was higher than that of newly treated patients (35.2%, <i>χ</i><sup>2</sup>=50.593, <i>P</i><0.001). The registered incidence rate in males (0.91/100 000) was higher than that in females (0.24/100 000, <i>χ</i><sup>2</sup>=80.566, <i>P</i><0.001). The age distribution showed that the highest incidence rate was in the age group≥60 years (0.96/100 000) and the lowest was in the age group 0-<45 years (0.31/100 000, <i>χ</i><sup>2</sup>=55.853, <i>P</i><0.001). From 2012 to 2020, Baoying County had the largest number of registered RR-PTB patients (44 cases), and its registered incidence rate (0.64/100 000) was only lower than that of Guangling District (0.98/100 000). The registered incidence rate of RR-PTB patients in Baoying County during 2016-2020 also increased significantly compared to 2012-2015 (<i>P</i>=0.001). Logistic regression was used to analyze the factors related to the treatment outcome of RR-PTB patients. The results showed that patients aged≥60 years and those classified as the re-treatment were risk factors for successful treatment of RR-PTB patients (<i>P</i><0.05). In summary, males, people aged≥60 years, patients classified as the re-treatment, and residents of Baoying County should be the key populations for RR-PTB epidemic prevention and control in Yangzhou City.
Authors
- Limei Zhu (ORCID: https://orcid.org/0000-0002-0448-8547)
- Bo Chen (ORCID: https://orcid.org/0000-0001-5161-879X)
- J C Li
- Lingling Wang (ORCID: https://orcid.org/0000-0003-0272-2974)
- Heng Wang (ORCID: https://orcid.org/0000-0002-1727-9226)
- Qinyu Zhao (ORCID: https://orcid.org/0000-0003-3543-7969)
Institutions
- Jiangsu Provincial Center for Disease Control and Prevention (CN)
- Nanjing Municipal Center for Disease Control And Prevention (CN)
- Yangzhou University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-11-06
- DOI
- https://doi.org/10.3760/cma.j.cn112150-20240102-00003
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article