Cost-effectiveness of implementing a genotype-guided de-escalation strategy in patients with acute coronary syndrome
A genotype-guided de-escalation strategy in patients with ACS was both cost-saving and yielded higher QALYs compared to standard DAPT, highlighting its potential for implementation in clinical practice. Trial registration: ClinicalTrials.gov identifier: NCT03823547.
Authors
- José P.S. Henriques (ORCID: https://orcid.org/0000-0002-8969-7929)
- Georgios J. Vlachojannis (ORCID: https://orcid.org/0000-0002-1641-3462)
- Melvyn Tjon Joe Gin (ORCID: https://orcid.org/0000-0001-9980-548X)
- Jurriën M. ten Berg (ORCID: https://orcid.org/0000-0001-5192-886X)
- Jorina Langerveld
- Yolande Appelman (ORCID: https://orcid.org/0000-0001-5241-7105)
- Ronald J Walhout (ORCID: https://orcid.org/0009-0007-6156-3842)
- Ron HN van Schaik (ORCID: https://orcid.org/0000-0003-1864-2151)
- Wouter J. Kikkert (ORCID: https://orcid.org/0000-0001-5160-2018)
- Nicoline J. Breet
- Lea Magdalena Dijksman (ORCID: https://orcid.org/0000-0001-9227-1390)
- Dean R.P.P. Chan Pin Yin (ORCID: https://orcid.org/0000-0002-7741-205X)
- Niels M R van der Sangen (ORCID: https://orcid.org/0000-0002-7661-9139)
- Wout W. A. van den Broek (ORCID: https://orcid.org/0000-0002-4083-9957)
- Rutger J. van Bommel (ORCID: https://orcid.org/0000-0002-5497-5992)
- Jaouad Azzahhafi (ORCID: https://orcid.org/0000-0003-4727-0481)
- Shabiga Sivanesan (ORCID: https://orcid.org/0009-0006-1534-7316)
Institutions
- Gelre Hospitals (NL)
- Erasmus MC (NL)
- University Medical Center (US)
- University Medical Center Utrecht (NL)
- Maastricht University (NL)
- St. Antonius Ziekenhuis (NL)
- Amsterdam Neuroscience (NL)
- Ziekenhuis Gelderse Vallei (NL)
- Ziekenhuis Rivierenland (NL)
- Tergooi (NL)
- Amsterdam University Medical Centers (NL)
- Rijnstate Hospital (NL)
- Amsterdam University of Applied Sciences (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- European Heart Journal - Cardiovascular Pharmacotherapy
- Published
- 2024-11-13
- DOI
- https://doi.org/10.1093/ehjcvp/pvae087
- Citations
- 9
- Primary Topic
- Antiplatelet Therapy and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 3.62
Funders
- AstraZeneca
- ZonMw