Genetic variants for Alzheimer's disease and comorbid conditions
Using a bivariate survival model approach, we identified genetic variants associated not only with ADRD, but also with comorbid conditions. Our utilization of dual-disease models represents a novel analytic strategy for uncovering shared genetic variants for multiple disease phenotypes.
Authors
- Frederick W. Unverzagt (ORCID: https://orcid.org/0000-0001-9297-1186)
- Andrew J. Saykin (ORCID: https://orcid.org/0000-0002-1376-8532)
- Sujuan Gao (ORCID: https://orcid.org/0000-0002-6741-6380)
- Hugh C. Hendrie (ORCID: https://orcid.org/0000-0002-7591-3176)
- Tatiana Foroud
- Liana Apostolova
- Dongbing Lai (ORCID: https://orcid.org/0000-0001-7803-580X)
- Minmin Pan (ORCID: https://orcid.org/0000-0001-5366-8387)
Institutions
- Indiana University School of Medicine
- Indiana University – Purdue University Indianapolis (US)
Publication Details
- Journal
- Journal of Alzheimer s Disease
- Published
- 2024-11-01
- DOI
- https://doi.org/10.1177/13872877241289054
- Citations
- 1
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 0.33
Funders
- Foundation for the National Institutes of Health
- National Institutes of Health