Novel Agonists of Adenosine Receptors in Animal Model of Acute Myocardial Infarction
Fibrosis and inflammatory components of MI reduced following treatment with agonist of adenosine receptor subtype A2A. Cardiac remodeling induced by LASSBio-1027 and LASSBio-1860 may be responsible for the improvement in cardiac function in AMI through the activation of A2A adenosine receptors.
Authors
- Tadeu L. Montagnoli (ORCID: https://orcid.org/0000-0003-1196-0149)
- Jaqueline da Silva (ORCID: https://orcid.org/0000-0003-3946-4753)
- Eliezer J. Barreiro (ORCID: https://orcid.org/0000-0003-1759-0038)
- Bianca Nascimento-Carlos
- Gisele Zapata-Sudo
- Rodolfo Couto Maia
- Fabricio Beltrame
Institutions
- Universidade Federal do Rio de Janeiro (BR)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2024-11-01
- DOI
- https://doi.org/10.2147/dddt.s464712
- Primary Topic
- Acute Myocardial Infarction Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro
- Instituto Nacional de Ciência e Tecnologia de Fármacos e Medicamentos