Short and Medium Chain Fatty Acids in a Cohort of Naïve Multiple Sclerosis Patients: Pre- and Post-Interferon Beta Treatment Assessment
nMS have a higher gut-inflammatory activity as seen by the caproic acid ratio as opposed to HC. In this cohort, IFNβ does not appear to modify the peripheral SCFA/MCFA levels after one year of treatment. The quantifications of peripheral SCFA/MCFA may prove to be a useful biomarker for gut-brain axis disruption in MS patients.
Authors
- Silvia Imre (ORCID: https://orcid.org/0000-0002-5186-9107)
- Ion Bogdan Mănescu (ORCID: https://orcid.org/0000-0001-6797-8757)
- Lénárd Farczádi (ORCID: https://orcid.org/0000-0002-0834-1614)
- Rodica Bălașa (ORCID: https://orcid.org/0000-0002-6254-2361)
- Smaranda Maier (ORCID: https://orcid.org/0000-0002-1834-582X)
- Laura Bărcuţean (ORCID: https://orcid.org/0000-0002-3033-0583)
Institutions
- Universitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș (RO)
- Spitalul Clinic Judetean de Urgenta Târgu Mureş (RO)
- Spitalul Clinic Judetean Mures (RO)
Publication Details
- Journal
- Biologics
- Published
- 2024-11-01
- DOI
- https://doi.org/10.2147/btt.s489523
- Citations
- 1
- Primary Topic
- RNA regulation and disease
- Type
- article
- Field-Weighted Citation Impact
- 0.23
Funders
- Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii