Role of CD38 in mediating the effect of Bacillus on acute pancreatitis: a study of mediated Mendelian randomization
This study is the first to uncover novel causal relationships between various intestinal flora and acute pancreatitis, emphasizing the mediating role of immune cell traits in the pathway from intestinal flora to AP. It also provides new evidence supporting the conditional pathogenicity of the Bacillus genus.
Authors
- Shaobiao Ke
- Junhao Xiao
- Mingjian Luo
- Yong Yan (ORCID: https://orcid.org/0009-0001-2568-1792)
- Jiulin Zhan
- Benliang Mao (ORCID: https://orcid.org/0009-0004-6135-8134)
- Tao Zhang (ORCID: https://orcid.org/0000-0001-5907-5312)
- Zhe Wang (ORCID: https://orcid.org/0000-0001-5407-4230)
- Zhiwei Li (ORCID: https://orcid.org/0009-0006-2550-7686)
- Bailin Wang (ORCID: https://orcid.org/0000-0001-5873-171X)
Institutions
- Shenzhen Maternity and Child Healthcare Hospital (CN)
- Dongguan People’s Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-11-15
- DOI
- https://doi.org/10.3389/fimmu.2024.1452743
- Citations
- 1
- Primary Topic
- Pancreatitis Pathology and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.57
Funders
- Natural Science Foundation of Guangdong Province