Customized Corneal Cross‐Linking with Microneedle‐Mediated Riboflavin Delivery for Keratoconus Treatment (Adv. Mater. 46/2024)
Customized Corneal Cross-Linking ln article number 2408136, Zhongxing Chen, Xingtao Zhou, Jinhai Huang, and co-workers introduce an innovative customized corneal cross-linking (CXL) therapy employing microneedles (MNs) for precise riboflavin (RF) delivery achieves notable CXL effects comparable to conventional epi-off CXL protocol and enhances visual function by flattening the corneal curvature in the treated zone. The frontispiece metaphorically represents the customized CXL process as being skillfully manipulated by magicians, highlighting the precision and efficacy of using MNs to deliver RF directly into the stroma and reinforce specific corneal zone.
Authors
- Aodong Chen
- Lingxin Chen (ORCID: https://orcid.org/0000-0002-3764-3515)
- Xingtao Zhou (ORCID: https://orcid.org/0000-0002-3465-1579)
- Keith M. Meek (ORCID: https://orcid.org/0000-0002-9948-7538)
- Jinhai Huang (ORCID: https://orcid.org/0000-0001-9952-3175)
- Xueyu Fu
- Siheng Li (ORCID: https://orcid.org/0000-0001-9582-3568)
- Xin Chen (ORCID: https://orcid.org/0000-0001-7706-4166)
- Rui Ning (ORCID: https://orcid.org/0009-0007-6516-5067)
- Tingting Chen (ORCID: https://orcid.org/0000-0002-2886-3751)
- Xiaoying Wang (ORCID: https://orcid.org/0000-0003-1029-0358)
- Hongxian Pan
- Mei Yang (ORCID: https://orcid.org/0000-0002-1784-570X)
- Zhongxing Chen
- Nan Zhao
- Qianfang Ye
- Yue Wu (ORCID: https://orcid.org/0009-0007-6219-8138)
- Jiawei Li (ORCID: https://orcid.org/0000-0002-6253-1582)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Wenzhou Medical University (CN)
- Affiliated Eye Hospital of Wenzhou Medical College (CN)
- Cardiff University (GB)
Publication Details
- Journal
- Advanced Materials
- Published
- 2024-11-01
- DOI
- https://doi.org/10.1002/adma.202470370
- Citations
- 2
- Primary Topic
- Corneal surgery and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.81