The effect of three urease inhibitors on H. pylori viability, urease activity and urease gene expression
In conclusion, higher concentrations of baicalin were needed to inhibit urease activity, compared to acetohydroxamic acid and ebselen. Baicalin, ebselen and acetohydroxamic acid reduced <i>H. pylori</i> viability. Therefore, these inhibitors should be further investigated as alternative treatments for <i>H. pylori</i> infection.
Authors
- Hanaa Shaalan
- Avi Peretz (ORCID: https://orcid.org/0000-0002-9012-6015)
- Maya Azrad (ORCID: https://orcid.org/0000-0002-0966-2575)
Institutions
- Bar-Ilan University (IL)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2024-11-15
- DOI
- https://doi.org/10.3389/fmicb.2024.1464484
- Citations
- 18
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article
- Field-Weighted Citation Impact
- 10.31