The effect of three urease inhibitors on H. pylori viability, urease activity and urease gene expression

In conclusion, higher concentrations of baicalin were needed to inhibit urease activity, compared to acetohydroxamic acid and ebselen. Baicalin, ebselen and acetohydroxamic acid reduced <i>H. pylori</i> viability. Therefore, these inhibitors should be further investigated as alternative treatments for <i>H. pylori</i> infection.

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Publication Details

Journal
Frontiers in Microbiology
Published
2024-11-15
DOI
https://doi.org/10.3389/fmicb.2024.1464484
Citations
18
Primary Topic
Helicobacter pylori-related gastroenterology studies
Type
article
Field-Weighted Citation Impact
10.31
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article

The effect of three urease inhibitors on H. pylori viability, urease activity and urease gene expression

Hanaa Shaalan, Avi Peretz, Maya Azrad
18 citations
Frontiers in Microbiology
Helicobacter pylori-related gastroenterology studies
10.31
article

The effect of three urease inhibitors on H. pylori viability, urease activity and urease gene expression

Hanaa Shaalan, Avi Peretz, Maya Azrad
article en
18 citations

Abstract

In conclusion, higher concentrations of baicalin were needed to inhibit urease activity, compared to acetohydroxamic acid and ebselen. Baicalin, ebselen and acetohydroxamic acid reduced <i>H. pylori</i> viability. Therefore, these inhibitors should be further investigated as alternative treatments for <i>H. pylori</i> infection.

Frontiers in MicrobiologyVol. 15
Bar-Ilan University (IL)
Openalex Percentile: Top 1%
Helicobacter pylori-related gastroenterology studies
10.31
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