Analyses of Xenorhabdus griffiniae genomes reveal two distinct sub-species that display intra-species variation due to prophages
Our findings suggest that phage-related genes drive the genomic diversity in closely related Xenorhabdus symbionts, and that these may underlie some of the traits most associated with the lifestyle and survival of entomopathogenic nematodes and their bacteria: virulence and competition. This study establishes a broad knowledge base for further exploration of not only the relationships between X. griffiniae species and their nematode hosts but also the molecular mechanisms that underlie their entomopathogenic lifestyle.
Authors
- Jemma McLeish
- Jennifer K. Heppert (ORCID: https://orcid.org/0000-0001-8602-414X)
- Ryan Musumba Awori (ORCID: https://orcid.org/0000-0002-8079-4968)
- Heidi Goodrich‐Blair (ORCID: https://orcid.org/0000-0003-1934-2636)
- Mengyi Cao (ORCID: https://orcid.org/0000-0002-3117-3401)
- Grischa Chen
Institutions
- Knoxville College (US)
- CABI Kenya (KE)
- University of Tennessee at Knoxville (US)
Publication Details
- Journal
- BMC Genomics
- Published
- 2024-11-15
- DOI
- https://doi.org/10.1186/s12864-024-10858-2
- Citations
- 3
- Primary Topic
- Entomopathogenic Microorganisms in Pest Control
- Type
- article
- Field-Weighted Citation Impact
- 1.62
Funders
- National Science Foundation
- California Institute of Technology
- Naresuan University
- Faculty of Medical Science, Naresuan University