Stability of closed and needle-punctured vials of Porvac® subunit vaccine against classical swine fever subjected to thermal stress

Porvac<sup>®</sup> is stable in all the experimental conditions tested, even after cap puncture, and retains the capacity to induce high titers of neutralizing antibodies, well above the threshold of protection. These results reinforce the robustness of the vaccine, and support its use as a very attractive alternative to modified live vaccines in developing countries endemic for CSF.

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Publication Details

Journal
BMC Veterinary Research
Published
2024-11-15
DOI
https://doi.org/10.1186/s12917-024-04354-8
Citations
1
Primary Topic
Animal Disease Management and Epidemiology
Type
article
Field-Weighted Citation Impact
0.57
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article

Stability of closed and needle-punctured vials of Porvac® subunit vaccine against classical swine fever subjected to thermal stress

Mary Karla Méndez-Orta, Paula Naranjo-Valdéz, Milagros Vargas-Hernández, Carlos A. Duarte et al.
1 citations
BMC Veterinary Research
Animal Disease Management and Epidemiology
0.57
article

Stability of closed and needle-punctured vials of Porvac® subunit vaccine against classical swine fever subjected to thermal stress

Mary Karla Méndez-Orta, Paula Naranjo-Valdéz, Milagros Vargas-Hernández, Carlos A. Duarte, Ania Cabrales, Marisela Suárez-Pedroso, María Pilar Rodríguez-Moltó, Yusmel Sordo-Puga, Alain Moreira-Rubio, Danny Pérez-Pérez, Talía Sardina-González, Elaine Santana-Rodríguez, Rosaili Mateu-Hernández, William Pena-Guimaraes, Mara Laura Hernández-García
article en
1 citations

Abstract

Porvac<sup>®</sup> is stable in all the experimental conditions tested, even after cap puncture, and retains the capacity to induce high titers of neutralizing antibodies, well above the threshold of protection. These results reinforce the robustness of the vaccine, and support its use as a very attractive alternative to modified live vaccines in developing countries endemic for CSF.

BMC Veterinary ResearchVol. 20(1)
Centro de Ingeniería Genética y Biotecnología (CU), University of Camagüey (CU)
Zero hunger
Openalex Percentile: Top 28%
Animal Disease Management and Epidemiology
0.57
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